EN
Liquid based cytology technique is an innovative cytological method that preserves exfoliated cells in a liquid medium, using specialized equipment to evenly distribute the cells and affix them to a slide to form a smear. This technique combines principles from mechanics, pneumatics, and fluid dynamics, employing fully automated equipment to produce uniform thin-layer specimens, which significantly reduces interference from blood, mucus, and inflammatory cells, thereby enhancing the clarity of cell observation.
The primary advantage of liquid based cytology technique lies in its ability to effectively separate impurities such as blood and mucus, creating smears with clear backgrounds and evenly distributed cells. This method significantly improves the detection rate of abnormal cells, marking a major technological advancement in the field of cytology. Common liquid based cytology preparation methods include:
Centrifugation Method: This method is simple and quick, typically requiring only the addition of a shaken sample to the preparation chamber, followed by centrifugation to complete the process.
Sedimentation Method: This method takes longer but results in higher cell density, with well-preserved three-dimensional structural characteristics.
Membrane Method: The preparation time for this method is between that of the centrifugation and sedimentation methods. However, since cells are pressed onto the slide, their morphology may be somewhat affected.
Cervical Cancer Screening
The liquid based cytology technique remains one of the primary methods for cervical cancer screening, particularly when combined with HPV co-testing, offering the highest sensitivity and specificity. This technique significantly reduces the false-negative rate, playing an essential role in early detection and providing strong protection for women's health.
Non-Gynecological Applications
In addition to its gynecological applications, the use of liquid based cytology technique is steadily increasing in non-gynecological fields. For example, fine needle aspiration cytology of the thyroid is useful for preoperative diagnosis of thyroid diseases, helping to avoid misdiagnosis and unnecessary surgery. Additionally, urine exfoliative cytology is used for screening urinary system tumors. More importantly, specimens obtained through LBC liquid based cytology are often an effective source for many molecular pathology tests and, in some cases, the only available source. This provides crucial support for the further classification and clinical treatment of tumors.
The innovative application of LBC liquid based cytology in cytological diagnosis not only increases the detection rate of abnormal cells but also significantly improves diagnostic accuracy. Whether in gynecological cancer screening or non-gynecological applications, the widespread use of liquid based cytology technique is continuously driving the intelligent and precise development of medical diagnostics. As a leading health technology enterprise, HealthSky is committed to providing more efficient and precise solutions to the medical field through liquid based cytology technique. By leveraging innovative technologies, HealthSky is making significant contributions to the advancement of global healthcare.
